Article
Determination of IDH1, IDH2, MGMT, TERT and ATRX Gene Mutations in Glial Tumors.
In vivo (Athens, Greece) - 1 Jan 2000
Yaltirik Cumhur Kaan, Yilmaz Seda Gulec, Ozdogan Selcuk, Bilgin Ezel Yaltirik, Barut Zerrin, Ture Ugur, Isbir Turgay
Abstract excerpt
BACKGROUND/AIM: The most frequent and dangerous kind of primary brain tumor is glioblastoma multiforme (GBM). The survival rates associated with GBM are very short and molecular markers for predicting survival are needed. The aim of our study was to evaluate isocitrate dehydrogenase 1 and 2 (IDH1, IDH2), telomerase reverse transcriptase (TERT), O-6- methylguanine-DNA methyltransferase (MGMT) and...
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