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Article

Human MTHFR-G1793A transition may be a protective mutation against male infertility: a genetic association study and in silico analysis.

Human fertility (Cambridge, England) - 1 Jun 2018

Karimian Mohammad, Hosseinzadeh Colagar Abasalt

Abstract excerpt

In this paper, we evaluate the association of the human methylenetetrahydrofolate reductase (MTHFR)-G1793A transition with male infertility using a case-control study, a meta-analysis and an in silico analysis. In the case-control study, 308 blood samples (169 infertile and 139 fertile men) were collected. MTHFR-G1793A genotyping was performed by PCR-RFLP. The study revealed a significant protective association...

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Source

Identifiers

PMID: 28270024
DOI: 10.1080/14647273.2017.1298161

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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