Article
Association of C677T transition of the human methylenetetrahydrofolate reductase (MTHFR) gene with male infertility.
Reproduction, fertility, and development - 1 Apr 2016
Karimian Mohammad, Colagar Abasalt Hosseinzadeh
Abstract excerpt
The human methylenetetrahydrofolate reductase (MTHFR) gene encodes one of the key enzymes in folate metabolism. This gene is located on chromosome 1 (1p36.3), which has 12 exons. The aim of the present study was to investigate the possible association of the two (C677T and A1298C) polymorphisms o...
Topics
- Adult
- Alleles
- Amino Acid Substitution
- Binding Sites
- Case-Control Studies
- Computational Biology
- Fertilization in Vitro
- Flavin-Adenine Dinucleotide
- Genetic Association Studies
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Infertility, Male
- Iran
- Kinetics
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Oligospermia