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Article

Trade-offs between microbial growth phases lead to frequency-dependent and non-transitive selection.

Proceedings. Biological sciences - 14 Feb 2018

Manhart Michael, Adkar Bharat V, Shakhnovich Eugene I

Abstract excerpt

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple life-history traits to selection is a critical question for evolutionary biology as we seek to predict the evolutionary fates of mutations. Here we use a model of microbial...

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Identifiers

PMID: 29445020
DOI: 10.1098/rspb.2017.2459
PMCID: PMC5829199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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