Article
Efflux Pump Overexpression Contributes to Tigecycline Heteroresistance in Salmonella enterica serovar Typhimurium.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Chen Yi, Hu Daxing, Zhang Qijing, Liao Xiao-Ping, Liu Ya-Hong, Sun Jian
Abstract excerpt
Bacterial heteroresistance has been identified in several combinations of bacteria and antibiotics, and it complicated the therapeutic strategies. Tigecycline is being used as one of the optimal options for the treatment of infections caused by multidrug-resistant Salmonella. This study investigated whether heterorresistance to tigecycline exists in a Salmonella enterica serovar Typhimurium strain harboring the...
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