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Article

Emergence of AcrAB-mediated tigecycline resistance in a clinical isolate of Enterobacter cloacae during ciprofloxacin treatment.

International journal of antimicrobial agents - 1 May 2010

Hornsey Michael, Ellington Matthew J, Doumith Michel, Scott Geoff, Livermore David M, Woodford Neil

Abstract excerpt

Tigecycline resistance remains rare amongst Enterobacteriaceae in the UK, as elsewhere, but has been associated with upregulation of the AcrAB efflux system. Using isolates of an Enterobacter cloacae strain that developed tigecycline resistance in vivo during ciprofloxacin therapy as well as labo...

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Identifiers

PMID: 20189357
DOI: 10.1016/j.ijantimicag.2010.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20189357-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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