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Article

Roles of ramR and tet(A) Mutations in Conferring Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates.

Antimicrobial agents and chemotherapy - 1 Aug 2017

Chiu Sheng-Kang, Huang Li-Yueh, Chen Hsi, Tsai Yu-Kuo, Liou Ci-Hong, Lin Jung-Chung, Siu L Kristopher, Chang Feng-Yee, Yeh Kuo-Ming

Abstract excerpt

Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, but increasing numbers of tigecycline-resistant K. pneumoniae isolates have been reported. The tigecycline resistance mechanisms in CRKP are undetermined. This study aimed to elucidate the mechanisms underlying tigecycline resistance in 16 tigecycline- and carbapenem-resistant K. pneumoniae (TCRKP)...

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Identifiers

PMID: 28533243
DOI: 10.1128/AAC.00391-17
PMCID: PMC5527587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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