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Article

Phenotypic and genomic characterization of tigecycline heteroresistance in carbapenem-resistant Klebsiella pneumoniae.

Microbiology spectrum - 3 Feb 2026

Tao Xingchen, Xia Yulian, Zhong Liping

Abstract excerpt

The presence of tigecycline heteroresistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) can compromise the efficacy of antimicrobial therapy. This study aimed to investigate the phenotypic and genomic characteristics of Tgc-HR in CRKP clinical isolates. A total of 52 non-repetitive CRKP isolates, all tigecycline-susceptible, were collected from January 2021 to December 2023. Tigecycline heteroresistance...

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Identifiers

PMID: 41504473
DOI: 10.1128/spectrum.03079-25
PMCID: PMC12889141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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