Article
Phenotypic and genomic characterization of tigecycline heteroresistance in carbapenem-resistant Klebsiella pneumoniae.
Microbiology spectrum - 3 Feb 2026
Tao Xingchen, Xia Yulian, Zhong Liping
Abstract excerpt
The presence of tigecycline heteroresistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) can compromise the efficacy of antimicrobial therapy. This study aimed to investigate the phenotypic and genomic characteristics of Tgc-HR in CRKP clinical isolates. A total of 52 non-repetitive CRKP...
Topics
- Tigecycline
- Klebsiella pneumoniae
- Anti-Bacterial Agents
- Microbial Sensitivity Tests
- Carbapenems
- Klebsiella Infections
- Humans
- Multilocus Sequence Typing
- Phenotype
- Plasmids
- Drug Resistance, Multiple, Bacterial
- Virulence Factors
- Genomics
- Genome, Bacterial
- Bacterial Proteins
- Carbapenem-Resistant Enterobacteriaceae
- Drug Resistance, Bacterial