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Article

Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection Fraction.

Journal of cardiovascular translational research - 1 Jun 2017

Katz Daniel H, Deo Rahul C, Aguilar Frank G, Selvaraj Senthil, Martinez Eva E, Beussink-Nelson Lauren, Kim Kwang-Youn A, Peng Jie, Irvin Marguerite R, Tiwari Hemant, Rao D C, Arnett Donna K, Shah Sanjiv J

Abstract excerpt

We sought to evaluate whether unbiased machine learning of dense phenotypic data ("phenomapping") could identify distinct hypertension subgroups that are associated with the myocardial substrate (i.e., abnormal cardiac mechanics) for heart failure with preserved ejection fraction (HFpEF). In the HyperGEN study, a population- and family-based study of hypertension, we studied 1273 hypertensive patients utilizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Echocardiography, Doppler

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Source

Identifiers

PMID: 28258421
DOI: 10.1007/s12265-017-9739-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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