Article

Multimodal Characterization of High-risk PH-HFpEF phenogroup with Right Ventricular Dysfunction: Vascular Mechanics and Myocardial Transcriptomics

2025-05-16

Abstract excerpt

<h4>Background</h4> Pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF) is a highly heterogeneous disease associated with right ventricular (RV) failure and adverse outcomes. Current diagnostic tools inadequately characterize pulmonary vascular disease and RV dysfunction, limiting treatment precision. We hypothesized that deep phenotyping—including invasive hemodynamics, advance...

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Literature Corpus work: be37aabc-3502-5db5-8470-2e2f7ba4deaa
DOI: 10.1101/2025.05.15.25327467

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