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Article

Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions.

Cardiovascular research - 3 Feb 2023

Peters Anthony E, Tromp Jasper, Shah Sanjiv J, Lam Carolyn S P, Lewis Gregory D, Borlaug Barry A, Sharma Kavita, Pandey Ambarish, Sweitzer Nancy K, Kitzman Dalane W, Mentz Robert J

Abstract excerpt

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with complex pathophysiology and manifestations. Phenomapping is the process of applying statistical learning techniques to patient data to identify distinct subgroups based on patterns in the data. Phenomapping has emerged as a technique with potential to improve the understanding of different HFpEF phenotypes. Phenomapping efforts...

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PMID: 36448685
DOI: 10.1093/cvr/cvac179
PMCID: PMC10144733

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