Rationale and design of the PACIFIC-PRESERVED (PhenomApping, ClassIFication and Innovation for Cardiac dysfunction in patients with heart failure and PRESERVED left ventricular ejection fraction) study.

doi:10.1016/j.acvd.2024.02.011

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Article

Rationale and design of the PACIFIC-PRESERVED (PhenomApping, ClassIFication and Innovation for Cardiac dysfunction in patients with heart failure and PRESERVED left ventricular ejection fraction) study.

Archives of cardiovascular diseases - 1 May 2024

Hulot Jean-Sébastien, Janiak Philip, Boutinaud Philippe, Boutouyrie Pierre, Chézalviel-Guilbert Frédérique, Christophe Jean-Joseph, Cohen Ariel, Damy Thibaud, Djadi-Prat Juliette, Firat Hüseyin, Hervé Pierre-Yves, Isnard Richard, Jondeau Guillaume, Mousseaux Elie, Pernot Mathieu, Prot Pierre, Tyl Benoit, Soulat Gilles, Logeart Damien

Abstract excerpt

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that is poorly defined, reflecting an incomplete understanding of its pathophysiology. AIM: To redefine the phenotypic spectrum of HFpEF. METHODS: The PACIFIC-PRESERVED study is a prospective multicentre cohort study designed to perform multidimensional deep phenotyping of patients diagnosed with HFpEF (left ventricular...

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PMID: 38644067
DOI: 10.1016/j.acvd.2024.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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