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Article

Rapid and stable changes in maturation-related phenotypes of the adult hippocampal neurons by electroconvulsive treatment.

Molecular brain - 2 Mar 2017

Imoto Yuki, Segi-Nishida Eri, Suzuki Hidenori, Kobayashi Katsunori

Abstract excerpt

Electroconvulsive therapy (ECT) is a highly effective and fast-acting treatment for depression. Despite a long history of clinical use, its mechanism of action remains poorly understood. Recently, a novel cellular mechanism of antidepressant action has been proposed: the phenotype of mature brain neurons is transformed to immature-like one by antidepressant drug treatments. We show here that electroconvulsive...

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Identifiers

PMID: 28253930
DOI: 10.1186/s13041-017-0288-9
PMCID: PMC5335812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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