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Article

Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells.

Cerebral cortex (New York, N.Y. : 1991) - 17 Oct 2016

Bosch Carles, Masachs Nuria, Exposito-Alonso David, Martínez Albert, Teixeira Cátia M, Fernaud Isabel, Pujadas Lluís, Ulloa Fausto, Comella Joan X, DeFelipe Javier, Merchán-Pérez Angel, Soriano Eduardo

Abstract excerpt

Significance Statement: The extracellular protein Reelin has an important role in neurological diseases, including epilepsy, Alzheimer's disease and psychiatric diseases, targeting hippocampal circuits. Here we address the role of Reelin in the development of synaptic contacts in adult-generated granule cells (GCs), a neuronal population that is crucial for learning and memory and implicated in neurological and...

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Share to Cell Adhesion Molecules, Neuronal
Share to Dendritic Spines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disks Large Homolog 4 Protein

Share to Imaging, Three-Dimensional

Share to Neurogenesis

Share to Neuroglia

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Share to Transduction, Genetic

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Identifiers

PMID: 27624722
DOI: 10.1093/cercor/bhw216
PMCID: PMC5066826

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