Article
Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.
PloS one - 1 Jan 2017
Vonk J M, Scholtens S, Postma D S, Moffatt M F, Jarvis D, Ramasamy A, Wjst M, Omenaas E R, Bouzigon E, Demenais F, Nadif R, Siroux V, Polonikov A V, Solodilova M, Ivanov V P, Curjuric I, Imboden M, Kumar A, Probst-Hensch N, Ogorodova L M, Puzyrev V P, Bragina E Yu, Freidin M B, Nolte I M, Farrall A M, Cookson W O C M, Strachan D P, Koppelman G H, Boezen H M
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This study aimed to identify novel genes that interact with ever active tobacco smoking in adult onset asthma. METHODS: We performed a genome-wide interaction analysis in six studies participating in the GABRIEL consortium following two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.