Article
Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits.
Human molecular genetics - 15 Jul 2016
Ballantyne Rachel L, Zhang Xuan, Nuñez Sara, Xue Chenyi, Zhao Wei, Reed Eric, Salaheen Danish, Foulkes Andrea S, Li Mingyao, Reilly Muredach P
Abstract excerpt
Long intergenic noncoding RNAs (lincRNAs) play important roles in disease, but the vast majority of these transcripts remain uncharacterized. We defined a set of 54 944 human lincRNAs by drawing on four publicly available lincRNA datasets, and annotated ∼2.5 million single nucleotide polymorphisms (SNPs) from each of 15 cardiometabolic genome-wide association study datasets into these lincRNAs. We identified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.