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Article

A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos.

Developmental cell - 27 Feb 2017

Oginuma Masayuki, Moncuquet Philippe, Xiong Fengzhu, Karoly Edward, Chal Jérome, Guevorkian Karine, Pourquié Olivier

Abstract excerpt

Mammalian embryos transiently exhibit aerobic glycolysis (Warburg effect), a metabolic adaptation also observed in cancer cells. The role of this particular type of metabolism during vertebrate organogenesis is currently unknown. Here, we provide evidence for spatiotemporal regulation of glycolysis in the posterior region of mouse and chicken embryos. We show that a posterior glycolytic gradient is established in...

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Identifiers

PMID: 28245921
DOI: 10.1016/j.devcel.2017.02.001
PMCID: PMC5403012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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