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Article

Eosinophil-associated TGF-β1 mRNA Expression and Airways Fibrosis in Bronchial Asthma

1 Sept 1997

Abstract excerpt

The histopathology of bronchial asthma is associated with structural changes within the airways, including subepithelial fibrosis, as well as chronic eosinophilic inflammation. The mechanisms responsible for this tissue remodeling, and in particular the role of inflammatory cells, remain to be established. Transforming growth factor-beta (TGF-beta) is a potent profibrotic cytokine which may contribute to the...

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PMID: 9308919
DOI: 10.1165/ajrcmb.17.3.2733

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