Article
Osteoprotegerin (OPG)/RANK-L system in juvenile idiopathic arthritis: is there a potential modulating role for OPG/RANK-L in bone injury?
The Journal of rheumatology - 1 May 2004
Masi Laura, Simonini Gabriele, Piscitelli Elisabetta, Del Monte Francesca, Giani Teresa, Cimaz Rolando, Vierucci Silvia, Brandi Maria Luisa, Falcini Fernanda
Abstract excerpt
OBJECTIVE: To evaluate serum levels of osteoprotegerin (OPG) and receptor activator of nuclear factor kB-ligand (RANK-L) in patients with juvenile idiopathic arthritis (JIA); to correlate these values with disease activity variables, radiological bone damage, and bone mass; and to correlate OPG gene polymorphisms with bone mass. METHODS: Eighty-four patients (66 girls and 18 boys) with JIA and 40 sex and...
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