TM6SF2 rs58542926 variant affects postprandial lipoprotein metabolism and glucose homeostasis in NAFLD.

doi:10.1194/jlr.M075028

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Article

TM6SF2 rs58542926 variant affects postprandial lipoprotein metabolism and glucose homeostasis in NAFLD.

Journal of lipid research - 1 Jun 2017

Musso Giovanni, Cipolla Ugo, Cassader Maurizio, Pinach Silvia, Saba Francesca, De Michieli Franco, Paschetta Elena, Bongiovanni Daria, Framarin Luciana, Leone Nicola, Berrutti Mara, Rosina Floriano, Corvisieri Stefania, Molinaro Federica, Sircana Antonio, Gambino Roberto

Abstract excerpt

Mechanisms underlying the opposite effects of transmembrane 6 superfamily member 2 (TM6SF2) rs58542926 C>T polymorphism on liver injury and cardiometabolic risk in nonalcoholic fatty liver disease (NAFLD) are unclear. We assessed the impact of this polymorphism on postprandial lipoprotein metabolism, glucose homeostasis, and nutrient oxidation in NAFLD. Sixty nonobese nondiabetic normolipidemic biopsy-proven...

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PMID: 28242789
DOI: 10.1194/jlr.M075028
PMCID: PMC5454511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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