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Article

Histologic transformation of EGFR mutant lung adenocarcinoma without exposure to EGFR inhibition.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 2017

Le Tri, Sailors Joseph, Oliver Dwight H, Mayer Melissa, Hoskin Sharon, Gerber David E

Abstract excerpt

Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28236979
DOI: 10.1016/j.lungcan.2017.01.005
PMCID: PMC5330183

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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