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Article

Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.

International journal of molecular sciences - 9 Apr 2022

Calabrese Fiorella, Pezzuto Federica, Lunardi Francesca, Fortarezza Francesco, Tzorakoleftheraki Sofia-Eleni, Resi Maria Vittoria, Tiné Mariaenrica, Pasello Giulia, Hofman Paul

Abstract excerpt

Patients with non-small cell lung cancer, especially adenocarcinomas, harbour at least one oncogenic driver mutation that can potentially be a target for therapy. Treatments of these oncogene-addicted tumours, such as the use of tyrosine kinase inhibitors (TKIs) of mutated epidermal growth factor receptor, have dramatically improved the outcome of patients. However, some patients may acquire resistance to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35456982
DOI: 10.3390/ijms23084164
PMCID: PMC9031930

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