Article
Conventional colon adenomas harbor various disturbances in microsatellite stability and contain micro-serrated foci with microsatellite instability.
PloS one - 1 Jan 2017
Lewitowicz Piotr, Gluszek Stanislaw, Koziel Dorota, Horecka-Lewitowicz Agata, Chrapek Magdalena, Wolak Przemyslaw, Klusek Justyna, Nasierowska-Guttmejer Anna
Abstract excerpt
INTRODUCTION: Colorectal cancer belongs to the most frequent occurring malignancies. A prediction of the clinical outcome and appropriate choice of neoadjuvant chemotherapy needs personalized insight to the main driving pathways. Because most CRCs have polyps as progenitor lesions, studying the pathways driving to adenomagenesis is no less important. GOALS: Our purpose was the evaluation of microsatellite...
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