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Article

Cell autonomous expression of CXCL-10 in JAK2V617F-mutated MPN.

Journal of cancer research and clinical oncology - 1 May 2017

Schnöder Tina M, Eberhardt Judith, Koehler Michael, Bierhoff Holger B, Weinert Sönke, Pandey Akhilesh Datt, Nimmagadda Subbaiah Chary, Wolleschak Denise, Jöhrens Korinna, Fischer Thomas, Heidel Florian H

Abstract excerpt

PURPOSE: Myeloproliferative neoplasms (MPN) are clonal disorders of hematopoietic stem- and progenitor cells. Mutation of Janus-Kinase 2 (JAK2) is the most frequent genetic event detected in Philadelphia-negative MPN. In advanced phases, the clinical hallmark of the disease is a striking inflammatory syndrome. So far, the cellular and molecular basis of inflammation is not fully understood. We, therefore, sought...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28233092
DOI: 10.1007/s00432-017-2354-1

Genes

CXCL10
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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