Article
Transmission of hepatitis E virus infection to human-liver chimeric FRG mice using patient plasma.
Antiviral research - 1 May 2017
Sayed Ibrahim M, Foquet Lander, Verhoye Lieven, Abravanel Florence, Farhoudi Ali, Leroux-Roels Geert, Izopet Jacques, Meuleman Philip
Abstract excerpt
Hepatitis E virus (HEV) is considered as an important pathogen in developing countries but there is growing evidence of its increasing significance and prevalence in the Western world. Although most acute HEV infections resolve spontaneously, chronicity has been observed in immunocompromised patients. The study of HEV has been hampered by the absence of practical animal models. Because the in vivo study of HEV...
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