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Article

A genetically humanized mouse model for hepatitis C virus infection.

Nature - 8 Jun 2011

Dorner Marcus, Horwitz Joshua A, Robbins Justin B, Barry Walter T, Feng Qian, Mu Kathy, Jones Christopher T, Schoggins John W, Catanese Maria Teresa, Burton Dennis R, Law Mansun, Rice Charles M, Ploss Alexander

Abstract excerpt

Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. Although xenotransplantation of immunodeficient mice with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21654804
DOI: 10.1038/nature10168
PMCID: PMC3159410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21654804-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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