Article
Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver.
Gut - 1 May 2017
Sayed Ibrahim M, Verhoye Lieven, Cocquerel Laurence, Abravanel Florence, Foquet Lander, Montpellier Claire, Debing Yannick, Farhoudi Ali, Wychowski Czeslaw, Dubuisson Jean, Leroux-Roels Geert, Neyts Johan, Izopet Jacques, Michiels Thomas, Meuleman Philip
Abstract excerpt
OBJECTIVE: The hepatitis E virus (HEV) is responsible for approximately 20 million infections per year worldwide. Although most infected people can spontaneously clear an HEV infection, immune-compromised individuals may evolve towards chronicity. Chronic HEV infection can be cured using ribavirin, but viral isolates with low ribavirin sensitivity have recently been identified. Although some HEV isolates can be...
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