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Glycosaminoglycans and mucopolysaccharidosis type III.

Frontiers in bioscience (Landmark edition) - 1 Jun 2016

Jakobkiewicz-Banecka Joanna, Gabig-Ciminska Magdalena, Kloska Anna, Malinowska Marcelina, Piotrowska Ewa, Banecka-Majkutewicz Zyta, Banecki Bogdan, Wegrzyn Alicja, Wegrzyn Grzegorz

Abstract excerpt

Mucopolysaccharidosis type III (MPS III), or Sanfilippo syndrome, is a lysosomal storage disease in which heparan sulfate is accumulated in lysosomes, as well as outside of cells, as the primary storage material. This disease is a complex of four conditions caused by dysfunctions of one of genes coding for lysosomal enzymes involved in degradation of heparan sulfate: SGSH (coding for heparan N-sulfatase) -...

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Identifiers

PMID: 27100513
DOI: 10.2741/4463

Genes

GNS
HGSNAT
NAGLU
SGSH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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