Article
Progranulin gene variation affects serum progranulin levels differently in Danish bipolar individuals compared with healthy controls.
Psychiatric genetics - 1 Jun 2017
Buttenschøn Henriette N, Nielsen Marit N, Thotakura Gangadaar, Lee Chris W, Nykjær Anders, Mors Ole, Glerup Simon
Abstract excerpt
OBJECTIVES: The identification of peripheral biomarkers for bipolar disorder is of great importance and has the potential to improve diagnosis, treatment and prognosis. Recent studies have reported lower plasma progranulin levels in bipolar individuals compared with controls and association with single nucleotide polymorphisms (SNPs) within the progranulin gene (GRN). In the present study, we investigated the...
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