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Article

Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF.

Translational psychiatry - 10 Nov 2015

Buttenschøn H N, Demontis D, Kaas M, Elfving B, Mølgaard S, Gustafsen C, Kaerlev L, Petersen C M, Børglum A D, Mors O, Glerup S

Abstract excerpt

Neurotrophic factors have been investigated in relation to depression. The aim of the present study was to widen this focus to sortilin, a receptor involved in neurotrophic signalling. The serum sortilin level was investigated in 152 individuals with depression and 216 control individuals, and eight genetic markers located within the SORT1 gene were successfully analysed for association with depression....

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Source

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Identifiers

PMID: 26556286
DOI: 10.1038/tp.2015.167
PMCID: PMC5068760

Genes

BDNF
SORT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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