Article
Further evidence for plasma progranulin as a biomarker in bipolar disorder.
Journal of affective disorders - 1 Mar 2014
Kittel-Schneider Sarah, Weigl Johannes, Volkert Julia, Geßner Alexandra, Schmidt Brigitte, Hempel Susanne, Kiel Tilman, Olmes David G, Bartl Jasmin, Weber Heike, Kopf Juliane, Reif Andreas
Abstract excerpt
BACKGROUND: A recent study suggested that progranulin (encoded by the fronto-temporal dementia risk gene GRN) plasma levels are decreased in bipolar disorder (BD). Replication of this finding is however lacking. METHODS: Progranulin plasma levels of bipolar patients (n=104) and healthy controls (n=80) were measured by enzyme-linked immunosorbent assay (ELISA). Participants were also genotyped for three single...
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