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HLA Amino Acid Polymorphisms and Kidney Allograft Survival

18 Feb 2017

Abstract excerpt

BACKGROUND: The association of HLA mismatching with kidney allograft survival has been well established. We examined whether amino acid (AA) mismatches (MMs) at the antigen recognition site of HLA molecules represent independent and incremental risk factors for kidney graft failure (GF) beyond those MMs assessed at the antigenic (2-digit) specificity. METHODS: Data on 240 024 kidney transplants performed between...

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PMID: 28221244
DOI: 10.1097/tp.0000000000001670

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