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Exome Sequencing and Prediction of Long-Term Kidney Allograft Function

29 Sept 2016

Abstract excerpt

Current strategies to improve graft outcome following kidney transplantation consider information at the human leukocyte antigen (HLA) loci. Cell surface antigens, in addition to HLA, may serve as the stimuli as well as the targets for the anti-allograft immune response and influence long-term graft outcomes. We therefore performed exome sequencing of DNA from kidney graft recipients and their living donors and...

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PMID: 27684477
DOI: 10.1371/journal.pcbi.1005088

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