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Article

Genetic regulation of differentially methylated genes in visceral adipose tissue of severely obese men discordant for the metabolic syndrome.

Translational research : the journal of laboratory and clinical medicine - 1 Jun 2017

Guénard Frédéric, Tchernof André, Deshaies Yves, Biron Simon, Lescelleur Odette, Biertho Laurent, Marceau Simon, Pérusse Louis, Vohl Marie-Claude

Abstract excerpt

A genetic influence on methylation levels has been reported and methylation quantitative trait loci (meQTL) have been identified in various tissues. The contribution of genetic and epigenetic factors in the development of the metabolic syndrome (MetS) has also been noted. To pinpoint candidate genes for testing the association of SNPs with MetS and its components, we aimed to evaluate the contribution of genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28219716
DOI: 10.1016/j.trsl.2017.01.002

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