Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

21 Feb 2018

Abstract excerpt

BACKGROUND: Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain unknown. In this study we identified alterations of DNA methylation influencing T2D pathogenesis, in subcutaneous and visceral adipose tissues, liver, and blood from individuals with obesity. METHODS: The study included individuals with obesity,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29466957
DOI: 10.1186/s12881-018-0542-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetesPMID 29466957Read ↗

DNA methylation and gene expression analysis in adipose tissue to identify new loci associated with T2D development in obesitySemantic proximity Read ↗

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetesSemantic proximity Read ↗

Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetesSemantic proximity Read ↗

DNA methylation in the pathogenesis of type 2 diabetes in humansSemantic proximity Read ↗

Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetesSemantic proximity Read ↗

DNA methylation landscapes in the pathogenesis of type 2 diabetes mellitusSemantic proximity Read ↗

DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patientsSemantic proximity Read ↗

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetesSemantic proximity Read ↗

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.Semantic proximity Read ↗

When Genes Wear Marks: Epigenomic Modulation in the Development and Progression of ObesitySemantic proximity Read ↗

DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic humanSemantic proximity Read ↗

Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individualsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.