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Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes.

Human heredity - 1 Jan 2016

Clark Michelle M, Chazara Olympe, Sobel Eric M, Gjessing Håkon K, Magnus Per, Moffett Ashley, Sinsheimer Janet S

Abstract excerpt

BACKGROUND/AIMS: Maternal and offspring cell contact at the site of placentation presents a plausible setting for maternal-fetal genotype (MFG) interactions affecting fetal growth. We test hypotheses regarding killer cell immunoglobulin-like receptor (KIR) and HLA-C MFG effects on human birth weight by extending the quantitative MFG (QMFG) test. METHODS: Until recently, association testing for MFG interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28214848
DOI: 10.1159/000456033
PMCID: PMC5557278

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