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Partitioning genetic effects on birth weight at classical human leukocyte antigen loci into indirect maternal and direct fetal components using structural equation modelling

2022-08-25

Abstract excerpt

Birth weight (BW), as a proxy for intrauterine growth, is influenced by both fetal and maternal genetic factors. Single nucleotide polymorphisms in the human leukocyte antigen (HLA) region in both maternal and fetal genomes have been robustly associated with BW in previous genetic association studies suggesting the involvement of classical HLA alleles in BW etiology. However, no study to date has partitioned the a...

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Literature Corpus work
0e37498c-aaca-510d-9788-bcdeb91b8ffc
DOI
10.1101/2022.08.23.505053
Open publication

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Partitioning genetic effects on birth weight at classical human leukocyte antigen loci into indirect maternal and direct fetal components using structural equation modellingDOI 10.1101/2022.08.23.505053
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