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Article

Concurrent MET copy number gain and KRAS mutation is a poor prognostic factor in pancreatobiliary subtype ampullary cancers.

Pathology, research and practice - 1 Apr 2017

Kwon Mi Jung, Kim Jeong Won, Jeon Jang Yong, Nam Eun Sook, Cho Seong Jin, Park Hye-Rim, Min Soo Kee, Seo Jinwon, Min Kyueng-Whan, Choe Ji-Young, Lee Hye Kyung

Abstract excerpt

Hepatocyte growth factor (HGF) and MET are candidates of targeted therapies for cancer patients. Although MET and HGF are commonly expressed in biliary tract cancers, their expression and gene copy number status and their association with KRAS mutations have not been investigated in pancreatobiliary-type ampullary adenocarcinomas (A-ACs), one of the aggressive periampullary cancers. MET and HGF expressions and...

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Source

Identifiers

PMID: 28214200
DOI: 10.1016/j.prp.2017.01.004

Genes

MET
HGF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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