Article
Survival in ampullary cancer: potential role of different KRAS mutations.
Surgery - 1 Feb 2015
Valsangkar Nakul P, Ingkakul Thun, Correa-Gallego Camilo, Mino-Kenudson Mari, Masia Ricard, Lillemoe Keith D, Fernández-del Castillo Carlos, Warshaw Andrew L, Liss Andrew S, Thayer Sarah P
Abstract excerpt
OBJECTIVE: The prognosis of ampullary adenocarcinoma (AA) usually is favorable; however, a subset of AA have poor biology and outcomes similar to pancreatic cancer. Patients in this subset will have early recurrence and death usually within 2 years. To date, there are no genetic markers to identify these patients. This study identifies the high-risk subset of AA and evaluates the mutational status of KRAS in...
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