Article
Attenuation of N-glycosylation causes polarity and adhesion defects in the C. elegans embryo.
Journal of cell science - 1 Apr 2017
Stevens Julia, Spang Anne
Abstract excerpt
The Caenorhabditiselegans early embryo is highly polarized, requiring sequestration of cytoplasmic polarity factors at the plasma membrane. This compartmentalization aids asymmetric distribution of lipids and proteins, which is partially responsible for the fates of the daughter cells. Since most plasma membrane proteins are glycosylated, we determined the effect of attenuation of N-glycosylation on cell...
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