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Matrix Metalloproteinase-9 and Synaptic Plasticity in the Central Amygdala in Control of Alcohol-Seeking Behavior.

Biological psychiatry - 1 Jun 2017

Stefaniuk Marzena, Beroun Anna, Lebitko Tomasz, Markina Olga, Leski Szymon, Meyza Ksenia, Grzywacz Anna, Samochowiec Jerzy, Samochowiec Agnieszka, Radwanska Kasia, Kaczmarek Leszek

Abstract excerpt

BACKGROUND: Dysfunction of the glutamatergic system has been implicated in alcohol addiction; however, the molecular underpinnings of this phenomenon are still poorly understood. In the current study we have investigated the possible function of matrix metalloproteinase-9 (MMP-9) in alcohol addiction because this protein has recently emerged as an important regulator of excitatory synaptic plasticity. METHODS:...

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Identifiers

PMID: 28190519
DOI: 10.1016/j.biopsych.2016.12.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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