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Article

HOXC10 suppresses browning of white adipose tissues

10 Feb 2017

Abstract excerpt

Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to determine the molecular factors involved in this process. Here we show that HOXC10, a homeobox domain-containing transcription factor expressed in subcutaneous white adipose tissue, is a suppressor of genes involved in browning white adipose tissue. Ectopic...

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PMID: 28186086
DOI: 10.1038/emm.2016.144

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