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Bi-directional interconversion of brite and white adipocytes.

Nature cell biology - 1 Jun 2013

Rosenwald Matthias, Perdikari Aliki, Rülicke Thomas, Wolfrum Christian

Abstract excerpt

Brown adipose tissue helps to maintain body temperature in hibernators, rodents and neonatal mammals by converting lipids and glucose into heat, thereby increasing energy expenditure. In addition to classical brown adipocytes, adult rodents-like adult humans-harbour brown-like adipocytes in the predominantly white adipose tissue. The formation of these brite (brown-in-white) adipocytes is a physiological response...

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Adipose Tissue
Cold Temperature
Energy Metabolism
Hot Temperature
Ion Channels

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Mitochondrial Proteins

T-Box Domain Proteins

Uncoupling Protein 1

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PMID: 23624403
DOI: 10.1038/ncb2740

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