Article
The association of the HLA-A*24:02, B*39:01 and B*39:06 alleles with type 1 diabetes is restricted to specific HLA-DR/DQ haplotypes in Finns.
HLA - 1 Apr 2017
Mikk M-L, Heikkinen T, El-Amir M I, Kiviniemi M, Laine A-P, Härkönen T, Veijola R, Toppari J, Knip M, Ilonen J
Abstract excerpt
BACKGROUND: We analysed the previously reported association of the HLA-A*24:02, B*18 and B*39 alleles with type 1 diabetes and diabetes associated autoimmunity in the Finnish population applying HLA-DR/DQ stratification. MATERIALS & METHODS: Haplotype transmission was analysed in 2424 nuclear families from the Finnish Paediatric Diabetes Register. Survival analysis was applied to study the development of islet...
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