Article
The HLA-B 3906 allele imparts a high risk of diabetes only on specific HLA-DR/DQ haplotypes.
Diabetologia - 1 Jul 2011
Baschal E E, Baker P R, Eyring K R, Siebert J C, Jasinski J M, Eisenbarth G S
Abstract excerpt
AIMS/HYPOTHESIS: We investigated the risk associated with HLA-B*39 alleles in the context of specific HLA-DR/DQ haplotypes. METHODS: We studied a readily available dataset from the Type 1 Diabetes Genetics Consortium that consists of 2,300 affected sibling pair families genotyped for both HLA alleles and 2,837 single nucleotide polymorphisms across the major histocompatibility complex region. RESULTS: The B*3906...
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