Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.

Scientific reports - 9 Feb 2017

Liau Brian, Jackman Christopher P, Li Yanzhen, Bursac Nenad

Abstract excerpt

We investigated whether the developmental stage of mouse cardiac fibroblasts (CFs) influences the formation and function of engineered cardiac tissues made of mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs). Engineered cardiac tissue patches were fabricated by encapsulating pure mESC-CMs, mESC-CMs + adult CFs, or mESC-CMs + fetal CFs in fibrin-based hydrogel. Tissue patches containing fetal CFs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Separation
Share to Cell Shape
Share to Coculture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media, Conditioned

Share to Mouse Embryonic Stem Cells

Share to Myocytes, Cardiac

Share to Tissue Engineering

Source

Open in PubMed Open full text

Identifiers

PMID: 28181589
DOI: 10.1038/srep42290
PMCID: PMC5299411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.PMID 28181589Read ↗

Progressive developmental cues from multiple cardiac cell types promote cardiomyocyte maturationSemantic proximity Read ↗

Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac MyocytesSemantic proximity Read ↗

Characterization of cardiac fibroblast-extracellular matrix crosstalk across developmental ages provides insight into age-related changes in cardiac repairSemantic proximity Read ↗

Developmental lineage of human pluripotent stem cell-derived cardiac fibroblasts affects their functional phenotype.Semantic proximity Read ↗

Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitorsSemantic proximity Read ↗

Cardiac Fibrosis and Cardiac Fibroblast Lineage-Tracing: Recent AdvancesSemantic proximity Read ↗

Sub-Confluent Culture of Mouse Embryonic Stem Cell-derived Ventricular Cardiomyocytes On & In Gels - Enhancement of Maturation Phenotype Relative to Tissue Culture Polystyrene via Enabling of Auxotonic ContractionSemantic proximity Read ↗

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.Semantic proximity Read ↗

Concise Review: Growing Hearts in the Right Place: On the Design of Biomimetic Materials for Cardiac Stem Cell DifferentiationSemantic proximity Read ↗

Coculture of Endothelial Cells with Human Pluripotent Stem Cell‐Derived Cardiac Progenitors Reveals a Differentiation Stage‐Specific Enhancement of Cardiomyocyte MaturationSemantic proximity Read ↗

Novel 3D culture system for study of cardiac myocyte developmentSemantic proximity Read ↗

Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived ProgenitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.