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Article

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.

Biomaterials - 1 Jul 2013

Zhang Donghui, Shadrin Ilya Y, Lam Jason, Xian Hai-Qian, Snodgrass H Ralph, Bursac Nenad

Abstract excerpt

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) provide a promising source for cell therapy and drug screening. Several high-yield protocols exist for hESC-CM production; however, methods to significantly advance hESC-CM maturation are still lacking. Building on our previous experience with mouse ESC-CMs, we investigated the effects of 3-dimensional (3D) tissue-engineered culture environment and...

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Identifiers

PMID: 23642535
DOI: 10.1016/j.biomaterials.2013.04.026
PMCID: PMC3660435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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