Article
The Degradome database: mammalian proteases and diseases of proteolysis.
Nucleic acids research - 1 Jan 2009
Quesada Víctor, Ordóñez Gonzalo R, Sánchez Luis M, Puente Xose S, López-Otín Carlos
Abstract excerpt
The degradome is defined as the complete set of proteases present in an organism. The recent availability of whole genomic sequences from multiple organisms has led us to predict the contents of the degradomes of several mammalian species. To ensure the fidelity of these predictions, our methods have included manual curation of individual sequences and, when necessary, direct cloning and sequencing experiments....
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