Natural Genetic Variation in the Caenorhabditis elegans Response to Pseudomonas aeruginosa.

doi:10.1534/g3.117.039057

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Article

Natural Genetic Variation in the Caenorhabditis elegans Response to Pseudomonas aeruginosa.

G3 (Bethesda, Md.) - 3 Apr 2017

Martin Natalia, Singh Jogender, Aballay Alejandro

Abstract excerpt

Caenorhabditis elegans responds to pathogenic microorganisms by activating its innate immune system, which consists of physical barriers, behavioral responses, and microbial killing mechanisms. We examined whether natural variation plays a role in the response of C. elegans to Pseudomonas aeruginosa using two C. elegans strains that carry the same allele of npr-1, a gene that encodes a G-protein-coupled receptor...

Topics

Animals
Behavior, Animal
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosome Mapping
Chromosomes
Genes, Suppressor
Genetic Association Studies
Genetic Variation
Loss of Function Mutation
Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymorphism, Single Nucleotide

Pseudomonas aeruginosa

RNA Interference

Receptors, Neuropeptide Y

Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 28179390
DOI: 10.1534/g3.117.039057
PMCID: PMC5386862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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