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Article

C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance.

Nature - 1 Oct 2020

Kaletsky Rachel, Moore Rebecca S, Vrla Geoffrey D, Parsons Lance R, Gitai Zemer, Murphy Coleen T

Abstract excerpt

Caenorhabditis elegans must distinguish pathogens from nutritious food sources among the many bacteria to which it is exposed in its environment1. Here we show that a single exposure to purified small RNAs isolated from pathogenic Pseudomonas aeruginosa (PA14) is sufficient to induce pathogen avoidance in the treated worms and in four subsequent generations of progeny. The RNA interference (RNAi) and...

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Source

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Identifiers

PMID: 32908307
DOI: 10.1038/s41586-020-2699-5
PMCID: PMC8547118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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